Grand Rounds Recap 1/13
/R1 CLINICAL KNOWLEDGE ON ESOPHAGEAL EMERGENCIES WITH DR. CONTINENZA
Boerhaave's syndrome: Full thickness esophageal perforation
Thought to be due to suddenly increased intra-esophageal pressure
60% of perforations thought to be iatrogenic, most commonly related to upper endoscopy
Chest X ray most of the time will have some abnormality, although it may just appear as a pneumonia. Pneumopericardium and obvious signs of mediastinitis may be rare on initial chest X ray, especially early in the disease process or with smaller esophageal tears and less mediastinal inoculation
CT scan is diagnostic modality of choice. If unavailable, upper GI series with Gastrograffin (less sensitive than barium though also less inflammatory reaction) is a better option that barium (greater sensitivity, more associated inflammation/potential for mediastinitis).
Treatment is broad spectrum antibiotics as a broad spectrum of oral and pharyngeal bacteria can be involved
Mortality is high and increases drastically with delays in diagnosis